The Gut Remembers: Israeli Researchers Uncover a Mechanism That Could Lead to Crohn’s and Colitis

A new study by the Weizmann Institute of Science, conducted in mice, organoids, and seven biopsies from colitis patients, found that a transient inflammation can leave a "memory" in the intercellular matrix, alter the fate of stem cells, and promote chronic inflammation. Dr. Moshe Biton, one of the study’s leaders: "Current treatments target only the outcome and not the root cause." The findings may point to a new direction for diagnosis, prevention, and therapy.

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